Artificial Intelligence and Endodontics 

AI demonstrated accuracy in endodontics when it came to prognostic and diagnostic assessments. The use of AI can improve the treatment strategy, which can improve the likelihood that endodontic treatment outcomes will be successful. In clinical applications, such as identifying root fractures, and periapical diseases, calculating working length, tracing apical foramen, analysing root morphology, and disease prediction, artificial intelligence (AI) is widely employed in endodontics. 


Dentistry has recently seen a rise in technical developments in the operations related to it, which has improved success rates and allowed for a better evaluation of treatment outcomes. One such modality that has begun to forge a path in the field of endodontics is artificial intelligence (AI). It has been found helpful in the medical field for bone age evaluation and the radiodiagnosis of cancer. It is a branch of technology that imitates human behaviours using devices and machinery. The primary module employed in dentistry comprises software-type algorithms, which are the virtual component of AI. The two main types of AI techniques are knowledge-based AI and data-driven AI. The foundation of knowledge-based AI is a top-down method of model in human knowledge and the self-reported concepts and knowledge that people use to figure out a solution to a problem. However, it has the drawbacks of taking too much time and requiring initial work to create an algorithm based on human understanding. In contrast to knowledge-based AI, data-driven AI, also called machine learning (ML), takes a bottom-up approach. 

Mathematical models are taught using data produced from human activities in data-driven AI. It is further divided into learning that is semi-supervised, unsupervised, and supervised. To discover the correlations between data instances, the supervised learning module uses methods like a decision tree and artificial neural networks (ANN). The vertebrate nervous system acts similarly to ANNs in that signals are received, followed by mathematical computation, and then the processed data is transmitted to the next higher level. The vertebrate nervous system is a highly interconnected network system. Through the application of multilayer convolutional neural networks, the unsupervised variant can examine data in great detail (CNN).

The combination of the aforementioned two approaches is semi-supervised learning. The ultimate goal of all of these techniques is to improve doctors’ capacity for handling intricate and substantial data. 

Developments and Performance of Artificial Intelligence Models Designed for Application in Endodontics: A Systematic Review

As an AI language model, I am unable to provide a comprehensive systematic evaluation of the scientific literature, but I can give a succinct summary of some of the major conclusions from a review of the advancements and effectiveness of AI models created for use in endodontics. The systematic review looked at endodontic research using AI that was published between 2010 and 2020.  

According to the review, AI has been applied to endodontics in a variety of ways, including diagnosis, treatment planning, and outcome prediction. The review’s key finding was that endodontic-specific AI models have demonstrated great levels of performance and accuracy across a range of applications. For instance, it has been discovered that AI models are quite good at spotting root canal irregularities and forecasting how treatment would proceed. The review also discovered that many studies have concentrated on proof-of-concept models, indicating that the application of AI in endodontics is still in its infancy.

 Yet, there is a huge opportunity for AI to enhance endodontic diagnosis and treatment outcomes, and additional study is required to fully understand its potential. According to the systematic study, AI has the potential to greatly increase the precision and effectiveness of endodontic treatments, resulting in better patient outcomes and lower treatment costs. To properly assess the performance and efficacy of AI models in endodontics, more investigation is necessary. 

Three innovations in endodontics

Here are three instances of the numerous advancements in endodontics over time: 

 Cone Beam Computed Tomography: (CBCT) is a 3D imaging technique, that has completely changed how endodontics diagnoses and plans treatments. A more precise diagnosis and treatment planning are made possible by the use of CBCT, which allows dentists to acquire highly detailed 3D images of the tooth and surrounding structures.

Nickel-Titanium Rotary Instruments: For root canal therapy, nickel-titanium (NiTi) rotary instruments have taken the role of conventional stainless steel hand instruments. Instrument breakage is less likely and treatment results are improved with NiTi instruments because they are more flexible and can travel the curved root canals more successfully. 

 Apex locators: Apex locators are electronic tools that precisely measure the length of the root canal using a low-voltage current. To determine the working length of the root canal, apex locators have taken the place of conventional radiography as the accepted technique. Because X-rays are no longer necessary, the process is safer and more comfortable for the patients. 

Laser technology: In endodontics, laser technology has been utilized to clean the root canal system of bacteria and debris. A minimally invasive treatment that effectively eliminates bacteria and other pathogens without causing damage to the surrounding tissues is laser-assisted disinfection. This can lower the risk of problems and increase the effectiveness of root canal therapies. 

Electronic anesthesia: Electronic anesthesia is a non-invasive technique used in endodontics for pain control. TENS reduces pain and suffering during the process by stimulating the nerves in the affected area with a low-level electrical current. By doing so, it may be possible to increase patient comfort and lessen the requirement for conventional local anesthetic. 

These developments have made endodontic therapy more precise, efficient, and patient-friendly. The discipline of endodontics is projected to continue to see innovation due to the continual development of new technology and methods, which will enhance patient outcomes and quality of life. 

Potential applications in Endodontics

Evaluation of the case’s difficulty: Diagnosing patients at risk for tooth structure loss and root caries can be done using predictive models that are based on data-driven AI. A recently published study that used ANN to estimate the degree of case difficulty found that the ML approach had a sensitivity of 94.96%.

 Root morphology analysis: Deep learning (DL) AI can identify additional roots in molars using cone-beam computed tomograms (CBCT). To evaluate their diagnostic performance, image patches from panoramic radiographs were segmented, enhanced, and then input into the DL system. The number of roots present was determined with a diagnostic accuracy of 86.9%.  

Periapical lesions: In a study by Orhan et al., it was determined whether the DL system accurately detected periapical pathosis using an AI system. The pathosis was then volumetrically measured on CBCT images using both manual and AI systems. The researchers concluded that AI systems were 92.8% accurate at detecting periapical lesions and were equivalent to manual segmentation methods. 6 A U-net architecture-based DL-based approach was found to be useful in another investigation to identify periapical pathosis. The CBCT was segmented using a method that classified each voxel into five categories: “lesion” (periapical lesion), “tooth structure,” “bone,” “restorative materials,” and “background.” Thereafter, the images were repeatedly separated. After that, the images were repeatedly separated and placed into the DL system to do cross-validation. The cumulative DICE index, which measures the similarity between two data sets—in this example, the manual approach and the DL-based method—between two data sets, was found to be 67% for the true positive lesions, making the detection accuracy of the DL-based methodology 93%. 

Cardiology: For occlusal and proximal lesions, respectively, a CNN-based AI system trained on a semantic segmentation method produced an area under the receiver-operating characteristic (ROC) curve of 83.6% and 85.6%, indicating excellent discrimination between the presence or absence of carious lesions.

Regenerative Endodontics: A determination coefficient of 0.81 was obtained when the predictive ability of stem-cell viability under various bacterial lipopolysaccharide concentrations was studied using a neuro-fuzzy system (a type of ANN), indicating that 81% of the predictive ability can be accounted for by the DL system. 

History Artificial Intelligence and Endodontics

It’s a recent breakthrough for endodontics to apply artificial intelligence (AI). Although artificial intelligence has been employed for many years in other medical specialties, endodontics is the most recent profession to see its effects. Early in the 1990s, the first studies on the application of AI in dentistry started to surface. This research centred on using artificial intelligence (AI) to identify and treat dental diseases like caries and periodontitis. Researchers have recently begun looking into the application of AI specifically in endodontics.  

One of the earliest research projects in this field, which looked at using an AI algorithm to identify pulpitis based on dental X-rays, was published in 2011. Many studies on the application of AI in endodontics have been done since then. Many facets of endodontic therapy, including diagnosis, treatment planning, and patient communication, have been the subject of these studies. 

For instance, a recent study examined the application of AI to evaluate cone beam computed tomography (CBCT) images to identify periapical lesions. The work was published in the Journal of Endodontics. According to the study, an AI algorithm was highly accurate at correctly diagnosing these lesions. 

Another study examined the use of AI to create individualized treatment regimens for individuals receiving root canal therapy, and it was published in the same journal. The researchers analysed patient records using a machine learning system to create personalized treatment strategies for each patient. 

Thus, while the application of AI in endodontics is still in its infancy, it shows significant promise for enhancing the precision and efficacy of endodontic treatment. It is expected that AI will become a more vital tool in the field of endodontics as technology develops and gets better. 

The challenges with AI

The following obstacles face the adoption of AI despite its profitable potential:  

 I.  Precisive training requires an enormous amount of data, which restricts its ability to diagnose uncommon disorders such as periapical lesions with origins other than endodontics. Just a lesser number of data patterns are available for the networks to “learn” from because healthcare data is not easily accessible due to ethical considerations such as maintaining patient privacy. 10 Moreover, the supplied data frequently lacks crucial details and is subject to bias in the selection process, which causes a particular data pattern to be overrepresented. 

 ii. The technology uses intricate methods, and its frequently unclear how datasets are chosen, vetted, and handled. This may lead to problems.  

 iii. Costly machine installation prevents this technology from being widely used in clinical settings daily. 12 In addition, software systems need to be updated frequently to meet changing demands. 

Future with Artificial Intelligence and Endodontics 

The future of endodontics and artificial intelligence (Robotic process automation (RPA) is bright and promising. These are a few potential future innovations that might change the industry:  

Treatment plans that are specifically tailored to each patient: Machine learning may examine a tremendous quantity of patient data, including genetics, lifestyle, and medical history. This may lessen the chance of problems and enhance the effectiveness of the treatment.

 Enhanced diagnostic accuracy: Intelligence could examine patient data and dental photos to identify endodontic illnesses earlier before symptoms appear. This might increase the precision of diagnosis and lessen the requirement for invasive therapies.  

Automated operations: Robots and equipment powered by AI may be able to carry out endodontic procedures more precisely and accurately than humans. This might lower the possibility of human error and enhance patient outcomes. 

Education of the patient: Automation robots and virtual assistants may enlighten patients about endodontic procedures, treatment alternatives, and post-treatment care. This might increase patient satisfaction while lowering the possibility of problems.  

Remote consultations: Computer vision might make it possible for patients to consult with endodontists remotely, giving them access to professional guidance from any location. Particularly in remote or impoverished locations, this might increase access to healthcare.  

Consequently, endodontics and AI have a promising future, and both patients and practitioners stand to gain much from it. 


With its potential uses in the diagnosis, prognosis, and prediction of treatment outcomes, experimental research on the applications of AI in the field of endodontics has opened new horizons. The use of AI as a great ally for dentists can be achieved by overcoming limitations in data gathering, interpretation, computational capacity, and moral concerns. Also, it appears that dental professionals are hesitant to implement AI in their clinical practices because they are dubious about the idea that it can substitute for doctors, even though it is well-established that nothing can replace the human brain or intelligence. AI can be used as an additional tool to improve clinical practice. Nonetheless, additional study is required to support its use and strengthen its applicability. 

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